Performance of Starch obtained from Dioscorea dumetorium as Disintegrant in Sodium Salicylate Tablets

Starch obtained from Dioscorea dumetorium was employed as a disintegrant in Sodium Salicylate based tablets at concentrations of 5 -15w/w. Properties of the starch evaluated include: bulk and tapped densities; water uptake by capillarity; Hausner's quotient and percent compressibility. Compound tablets were evaluated for hardness; friability; disintegration time and dissolution rate. Batches of tablets containing equivalent concentrations of AC-di-sol or maize starch were employed as standards. Results obtained indicate that Dioscorea dumetorium starch performed as much better as a disintegrant in sodium salicylate tablets as maize starch but less than Ac-di-sol

Some pharmacological properties of Synclisia scabrida II.

The effect of the aqueous extract of S. scabrida on behaviour, and as an analgesic and antiulcer agent were studied. The extracts did not produce significant central nervous system action, or analgesia but had significant antiulcer activity against aspirin induced ulcer. The extract showed anticholinergic and antihistaminergic properties.